Earlier in his career, Frank Oz was known for his creative collaborations with the famed Jim Henson performing many Muppet characters, including Miss Piggy, Fozzie Bear, and Animal, as well as Bert, Grover, and Cookie Monster. Some projects Henson and Oz worked on included Sesame Street, Saturday Night Live, and The Muppet Show. He has also performed the unforgettable Jedi Master, Yoda, in all Star Wars films.

Oz has directed The Dark Crystal (With Jim Henson), The Muppets Take Manhattan, Little Shop of Horrors, Dirty Rotten Scoundrels, Housesitter, What About Bob, Indian in the Cupboard, In and Out, The Score, Bowfinger, Stepford Wives, Death at a Funeral, and In & Of Itself.

Among his many honors, Oz is the recipient of four Emmy® Awards. He has received two George Foster Peabody Awards, The American Comedy's Creative Achievement Award, The Art Directors Guild Award, The Saturn Lifetime Achievement Award, three gold and two platinum records, and other Awards and honors.